ABSTRACT
El tumor triquilemal proliferante es una dermatosis tumoral poco frecuente y derivada de la capa externa de la raíz del folículo piloso. Generalmente, es de características benignas, tiende a ser recidivante y se han reportado casos de transformaciones malignas en la bibliografía mundial. El caso trata de una paciente femenina de 59 años, con una neoformación exofítica nodular lobulada de crecimiento lento en piel cabelluda, de 5 años de evolución, con recidivas después de 3 cirugías. No se documentó compromiso óseo ni cerebral en los estudios de gabinete. La biopsia mostró proliferación de nidos de células escamosas en dermis, separados por bandas de tejido fibroso de la epidermis. El abordaje quirúrgico es el tratamiento de elección de esta patología.
Proliferating trichilemmal tumor is a rare cutaneous neoplasm originating from the outer root sheath of a hair follicle. It is usually benign, tends to recur and cases of malignant transformations have been reported in worldwide literature. Our case relates to a 59-year-old female with a slow-growth exophytic nodular lobulated tumor with a 5-year development and recurrences after 3 previous surgeries. Clinical imaging showed no skull or cerebral involvement. The biopsy showed proliferating squamous cell clusters in dermis separated by fibrous tissue in the epidermis. Surgical excision is the best choice of treatment for this disease.
Subject(s)
Humans , Adult , Female , Epidermal Cyst , Neoplasms , Pilomatrixoma , ScalpABSTRACT
No abstract available.
ABSTRACT
Proliferating trichilemmal tumor (PTT) is an uncommon neoplasm originated from the outer root sheath of a hair follicle. Malignant transformation occurs occasionally in proliferating trichilemmal tumors, which can be manifested by sudden rapid growths. Histologically, the malignant proliferating trichilemmal tumors (MPTTs) have shown severe nuclear atypia, marked cellular pleomorphism with atypical mitoses, dyskeratotic cells and infiltrating margins. Squamous cell carcinoma (SCC) should be differentiated with MPTT which indicates characteristic trichilemmal keratinization. Large tumor is considered as a risk factor of metastasis in SCC, but the relationship between tumor size and metastasis in the MPTT is not yet clarified. In this report, two patients have large erythematous nodules with focal ulceration and necrosis on their scalps and were diagnosed as MPTT. Despite the large sizes of the tumors, there were no evidences of metastases. Herein, we report 2 cases of the large MPTT which are presented without metastasis.
Subject(s)
Humans , Carcinoma, Squamous Cell , Hair Follicle , Mitosis , Necrosis , Neoplasm Metastasis , Risk Factors , Scalp , UlcerABSTRACT
Proliferating trichilemmal tumor is a rare benign tumor of skin appendage. It is usually solitary, more common in women after the fourth decade of life, and almost exclusively confined to the scalp and back of the neck. We report herein an unusual case of proliferating trchilemmal tumor which occurred on the knee.
Subject(s)
Female , Humans , Bursitis , Knee , Neck , Scalp , SkinABSTRACT
PURPOSE: To report the case of recurred malignant proliferating trichilemmal tumor on scalp METHODS: Case report and literature review RESULTS: A 40-year-old man presented with a recurred malignant proliferating trichilemmal tumor, which developed on the occipital area. It was 8 x 9 x 4.5 cm in size, protruded, firm and non-tender mass. This tumor was widely excised including normal skin margin and pericranium. Immediate reconstruction using free latissimus dorsi muscle flap and skin graft were done. Histopathologic examination revealed abrubt, compact trichilemmal keratinization in the central area of lobular epithelial proliferation. CONCLUSION: There has been no recurrence of tumor during follow-up period of nine months without adjuvant chemotherapy or radiotherapy.
Subject(s)
Adult , Humans , Chemotherapy, Adjuvant , Follow-Up Studies , Radiotherapy , Recurrence , Scalp , Skin , Superficial Back Muscles , TransplantsABSTRACT
Proliferating trichilemmal cyst(proliferating trchilemmal tumor, PTC) most commonly occurs in the scalp and is generally benign. Malignant transformation of PTC is rare, and the appearance of a spindle cell(sarcomatoid) carcinoma is extremely rare. The authors experienced a case of malignant proliferating trchilemmal tumor with spindle cell carcinoma on the scalp in a 41-year-old male. The tumor was widely resected and covered with split thickness skin graft after Terudermis(R) graft. Imaging studies and fine needle aspiration cytology showed no regional lymph node involvement or distant matastasis.
Subject(s)
Adult , Humans , Male , Biopsy, Fine-Needle , Lymph Nodes , Scalp , Skin , TransplantsABSTRACT
Malignant proliferating trichilemmal tumor is a rare neoplasm derived from the outer root sheath of the hair follicle. We report a 64-year-old woman with nodular mass in her scalp of for 10 years. Despite surgical removal of the mass, the residual lesion grew with ulceration. In fine needle aspiration, malignant cells were detected. Histological examination of the skin lesion revealed a lobulated tumor exhibiting keratinization beneath the epidermis. In some area, cord of atypical cells infiltrating surrounding tissue, stromal desmoplasia, mitotic figures were seen. For treatment wide surgical excision and skin graft were done.
Subject(s)
Female , Humans , Middle Aged , Biopsy, Fine-Needle , Epidermis , Hair Follicle , Scalp , Skin , Transplants , UlcerABSTRACT
A 32-year-old man was admitted to our hospital due to a headache. A brain CT and MRI showed a parenchymal mass in the right temporoparietooccipital lobe and histopathological specimens demonstrated a proliferating trichilemmal tumor (PTT). Two years prior to experiencing headache, the man had a round mass localized in the right suboccipital scalp which recurred after wide excisions and was found to be PTT. There was no evidence of tumor recurrence at the scalp during the period the man first began experiencing headache. Although PTT usually occurrs at the scalp, direct invasion into the brain is very rare. We report a patient with malignant PTT who developed brain parenchymal inva-sion, which was supported by neuroradiological and histopathological findings.
Subject(s)
Adult , Humans , Brain , Headache , Magnetic Resonance Imaging , Recurrence , ScalpABSTRACT
The cytologic finding of proliferating trichilemmal tumor is not well documented and have difficulties in the cytological analysis of the fine needle aspirates. This rare dermatopathologic entity may be encountered during aspiration biopsy of subcutaneous masses, and is, occasionally, confused with other neoplasm, particulary squamous carcinoma owing to its close cytological resemblance. We report a case of proliferating trichilemmal tumor in the left breast. The patient is a woman and had a lump in the breast for 20 years. Fine needle aspiration revealed a few small clusters of squamoid cells in the background of amorphous and calcified material. After excisional biopsy, the mass was confirmed as proliferating trichilemmal tumor. The main cytologic features discriminating squamous cell carcinoma were bland nature of epithelial cells, absence of atypical dyskeratotic cells, and rich amount of amorphous material.
Subject(s)
Female , Humans , Biopsy , Biopsy, Fine-Needle , Biopsy, Needle , Breast , Carcinoma, Squamous Cell , Epithelial Cells , NeedlesABSTRACT
Proliferating trichilemmal tumor is a relatively uncommon tumor which develops preferentially as a solitary tumor on the scalp of elderly women. Histologically, the tumor i epresents a proliferation of the outer root sheath epithelium in a characteristic pattern, but the presense of cellular atypia, dyskera.totic cells and mitotic figures may lead to a false impression of squamous cell carcinoma. We report a case of proliferating trichliemmal tumor in a 70-yeiir-old male who presented with a slowly growing tumor on his right inguinal area for 2 years. This case is unusual in that the tumor occurred on the inguinal are anoher than the scalp in a male.
Subject(s)
Aged , Female , Humans , Male , Carcinoma, Squamous Cell , Epithelium , ScalpABSTRACT
The proliferating trichilemmal tumor (PTT) is a rare, usually benign, tumor arising from the outer root sheath of the hair follicle. The usual clinical presentation is in a form of subcutaneous nodule in the scalp of elderly woman. Histopathologically, characteristic proliferation of the outer root sheath epithelium such as trichilemmal keratinization and nodular organization is observed as well as cellular atypia which may lead to impression of malignancy. The author report a case of proliferating trichilemmal tumor arisen in the thigh of a 24-year-old male within duration of 3 months which is quite an unusual clinical presentation.
Subject(s)
Aged , Female , Humans , Male , Young Adult , Epithelium , Hair Follicle , Scalp , ThighABSTRACT
Proliferating trichilemmal tumor is relatively rare, and is generally considered to be a benign tumor that can be histologically mistaken for well-differentiated squamous cell carcinoma. The proliferating trichilemmal tumor is thought to be a tumor with differentiation toward the hair structure because the characteristic trichilemmal keratinization in this tumor is analogous to that of the outer root sheath of anagen hair or the trichilemmal sac surrounding catagen hair. We report four cases of proliferating trichilemmal tumor removed by surgical excision.
ABSTRACT
Proliferating trichilernmal tumor is a rare benign solitary tumor that may be histopathologically misinterpreted as squarnous cell carcinoma. It affects frequently the scalp of elderly women. We present herein a case of proliferating trichilemmal tumor in an 87-year-old male who had had a slowly growing tumor on the scalp for 30 years.